Sommer
A, Tielsch JM, Katz J, Quigley HA, Gottsch JD, Javitt JC, Martone JF, Royall
RM, Witt KA, Ezrine S.
Racial differences in the cause-specific prevalence of blindness in
east Baltimore.
N Engl J Med 1991;325(20):1412-7.
(Comment in: N Engl J Med. 1991;325(20):1440-2.)
The purpose of this study was to evaluate the causes and distribution
of blindness in a locally representative sample of subjects aged 40 years
and older and to assess the basis for the higher rate of bilateral blindness
in blacks compared with whites. Of the 5,308 subjects screened in East
Baltimore, 64 were blind in both eyes.
The patterns and causes of blindness differed for blacks and whites.
The major causes of blindness among blacks were unoperated cataract (27%)
and primary open-angle glaucoma (19%), and the major causes among whites
were macular degeneration (30%) and unoperated senile cataract (13%).
Forty-one percent of the blind blacks were less than 65 years of age,
almost twice the proportion of whites. The high rate of blindness in younger
blacks was due to glaucoma, trauma, diabetes, and hereditary retinopathy.
The authors point out two important race-related patterns. First, vision
in 41 of the 128 blind eyes could definitely or probably be improved by
appropriate management which generally included cataract surgery, and
cataract surgery was likely to benefit a greater number of blacks than
whites. Second, with regard to primary open-angle glaucoma, shown to be
a major cause of blindness in blacks, it was not likely that access to
health care was associated with glaucoma blindness in this sample because
equal proportions of subjects with glaucoma were aware that they had the
disease. The authors suggested that compliance and the effectiveness of
therapy might have varied between the races.