This article outlines the successes of the National Minority Organ Tissue Transplant Education Program (MOTTEP). The development of MOTTEP stemmed from the research initiated in 1982 by Dr. Clive O. Callender into those behavioral factors that inhibit organ and tissue donations among African Americans. The absolute number of African American donors, by several indices, have increased by striking percentages since the initiation of this effort; the relative number compared to whites remained roughly equal. A preliminary assessment of MOTTEP seminars indicated that, although there were significant changes in knowledge and attitude toward organ transplantation among African Americans attending seminars, their willingness to sign donor cards tended to change less. Thus, based on this information, MOTTEP has further strengthened its use of various strategies to increase the number of organ donors, particularly among minority populations.