Am
J Respir Crit Care Med 2000 Sep;162(3 Pt 1):873-7.
Risk factors for pediatric asthma. Contributions of poverty, race, and urban
residence.
Aligne CA, Auinger P, Byrd RS, Weitzman M.
Strong Children's Research Center, Rochester General Hospital, and American
Academy of Pediatrics Center for Child Health Research, Rochester, New
York, USA. andrew.aligne@viahealth.org
The Child Health Supplement to the 1988 National Health Interview Survey
was used to examine parent-reported current asthma among a nationally
representative sample of 17,110 children zero to 17 yr of age. Numerous
demographic variables were analyzed for independent associations with
asthma using modified stepwise logistic regression, with models including
specific combinations of risk factors. Black children had higher rates
of asthma than did white children in unadjusted analyses, but after controlling
for multiple factors, black race was not a significant correlate of asthma
(adjusted odds ratio = 0.87, 95% CI = 0.63 to 1.21). Compared with nonurban
white children, urban children, both black and white, were at significantly
increased risk of asthma: urban and black (adjusted OR = 1.45, 95% CI
= 1.14 to 1.86), urban and white (adjusted OR = 1.22, 95% CI = 1.01 to
1.48), whereas nonurban black children were not: nonurban and black (adjusted
OR = 1.15, 95% CI = 0.83 to 1.61). Similarly, compared with nonurban,
nonpoor children, urban and poor (adjusted OR = 1.44, 95% CI = 1.05 to
1.95), urban and nonpoor (adjusted OR = 1.22, 95% CI = 1.004 to 1.48),
urban children, both poor and nonpoor, were at significantly increased
risk of asthma, whereas nonurban poor children were not: nonurban and
poor (adjusted OR = 1.03, 95% CI = 0.72 to 1.48). These results suggest
that the higher prevalence of asthma among black children is not due to
race or to low income per se, and that all children living in an urban
setting are at increased risk for asthma.
PMID: 10988098 [PubMed - indexed for MEDLINE]