Arch
Intern Med 1993 Dec 27;153(24):2781-6
Racial variations in the rates of carotid angiography and endarterectomy
in patients with stroke and transient ischemic attack.
Oddone EZ, Horner RD, Monger ME, Matchar DB.
Health Services Research and Development, Veterans Affairs Medical Center,
Durham, NC.
BACKGROUND: Carotid endarterectomy is emerging as the
treatment of choice for patients with symptomatic carotid artery stenosis
at low operative risk. We sought to determine if racial variations in
the rate of carotid angiography and endarterectomy exist in the Veteran
Affairs health care system among patients who are insulated from the cost
of their care.
METHODS: From a national database of all hospitalizations
at Veterans Affairs medical centers, we identified a cohort of patients
with diagnoses of stroke or transient ischemic attack who were likely
to be candidates for carotid angiography and endarterectomy. We used logistic
regression to determine if the patient's race was associated with receiving
carotid angiography and endarterectomy, after adjusting for patient's
age, degree of eligibility for Veterans Affairs care, socioeconomic status,
comorbidities associated with hospital admission, and geographic region
of the hospital.
RESULTS: Of the 35 922 veterans in the cohort, 3535 (9.8%)
underwent angiography during the study period and 1249 (3.5%) had carotid
endarterectomy. Blacks constituted 18.2% of the patients with a history
of stroke or transient ischemic attack, 9.8% of the patients having angiography,
but only 4.2% of the patients undergoing carotid endarterectomy. Whites
constituted 77.1% of the patients with a history of stroke or transient
ischemic attack, 86.1% of the patients receiving angiography, and 93.0%
of those having carotid endarterectomies. After adjusting for confounding
variables, black patients continued to have a significantly lower likelihood
than white patients of undergoing angiography (risk ratio = 0.47; 95%
confidence interval = 0.42, 0.53) and subsequent endarterectomy (risk
ratio = 0.28; 95% confidence interval = 0.20, 0.38).
CONCLUSIONS: Socioeconomic status and access to care
within a large managed health care system do not fully explain racial
differences in the rate of carotid angiography and endarterectomy. Either
referral bias for evaluation for carotid endarterectomy or racial differences
in the extent and location of cerebrovascular disease are more important
explanations for the observed racial variations.
PMID: 8257254 [PubMed - indexed for MEDLINE]