Goff
DC Jr, Feldman HA, McGovern PG, Goldberg RJ, Simons-Morton DG, Cornell CE,
Osganian SK, Cooper LS, Hedges JR.
Prehospital delay in patients hospitalized with heart attack symptoms
in the United States: the REACT trial. Rapid Early Action for Coronary Treatment
(REACT) Study Group.
Am Heart J 1999;138(6 Pt 1):1046-57.
The purpose of this study was to examine factors associated with pre-hospital
delay time in patients hospitalized for evaluation of heart attack symptoms.
Data for this study were drawn from the Rapid Early Action for Coronary
Treatment (REACT) study, a multicenter, randomized, community trial designed
to test a community intervention to reduce the duration of pre-hospital
delay in persons having heart attack symptoms. Communities were located
in Alabama, Louisiana, Massachusetts, Minnesota, North Dakota, Oregon,
South Dakota, Texas, Washington, and Wisconsin; there were 44 hospitals.
The data was collected from December 1995 to March 1996.
The distribution of delay times for 2,726 patients hospitalized for suspected
acute cardiac ischemia and discharged with a CHD-related diagnosis was
right skewed with a median of two hours and a mean of five hours. With
regard to race, the pre-hospital delay was longer among Hispanics and
non-Hispanic blacks than for non-Hispanic whites. Multivariate analyses
showed that the delay was significantly longer among non-Hispanic blacks
than among non-Hispanic whites (by 43 minutes). It was also longer among
older patients (by 14 minutes for each 10-year age increment), Medicaid
recipients versus the privately insured (by 41 minutes), the privately
insured versus Medicare recipients (by 27 minutes), and patients not arriving
by ambulance (by 47 minutes).
It is noteworthy that there were patterns to the missing data that should
be considered when interpreting these data. Specific to race analyses,
data were missing substantially more for Hispanics and non-Hispanic blacks
than for non-Hispanic whites.
The authors do not discuss reasons for the racial patterns, although
they cite their previous study of overall deficiencies and subgroup deficits
in knowledge of health attack symptoms in the general population of these
communities (Goff DC, et al. Knowledge of health attack symptoms in a
population survey in the US: REACT. Ach Intern Med 1998; 158:2329-2338).
They note that “these knowledge deficits mirror the differences
in pre-hospital delay time observed in this study. Deficiencies in knowledge
as well as {maladaptive coping strategies, misattribution of the symptoms
to a potentially less serious cause, embarrassment about being wrong,
or other barriers} probably contribute to the delays observed in this
and other studies.”