Gillum
RF, Mussolino ME, Madans JH.
Coronary heart disease incidence and survival in African-American women
and men. The NHANES I Epidemiologic Follow-up Study.
Ann Intern Med 1997;127(2):111-8.
This prospective study analyzed data from the National Health and Nutrition
Examination Survey (NHANES) I Epidemiologic Follow-up Study, a longitudinal
study of participants in the nationwide survey from 1971 to 1975 of the
non-institutionalized population of the United States. For a cohort with
no history of coronary heart disease (CHD) at baseline, the study sought
to determine if the incidence of coronary procedures during or after hospitalization
differed between blacks and whites.
The investigators found that the “incidence of coronary artery
bypass grafting or angioplasty was 27.8 (n= 245) per 1000 person-years
in white persons but only 5.1 (n = 6) per 1000 person-years in African-American
persons (ratio 5.5). The incidence of cardiac catheterization or coronary
angioplasty was 40.3 (n = 355) per 1000 person-years in white persons
and 25.6 (n = 30) per 1000 person-years in African-American persons (ratio
1.6). For any of these procedures, the rates were 47.0 (n= 414) per 1000
person-years in white persons and 26.5 (n=31) per 1000 person-years in
African-American persons (ratio, 1.8).”
In sum, African-Americans were 60% less likely to undergo any of these
procedures any date after first hospitalization for CHD. The RR for any
type of revascularization was 0.15 (CI, 0.02 to 1.05) and, for angiography
or catheterization, the RR was 0.53 (CI, 0.21 to 1.34). Adjustment for
multiple risk factors did not affect these results. These findings are
coupled with the conclusion that, in comparison to white persons, the
age-adjusted risk for coronary heart disease is 1.76 times higher in black
women, with an age-adjusted mortality rate that is 2.25 times higher.
“On the basis of these findings,” the authors recommend that
“physicians must take extra care to promote the appropriate use
of cardiac catheterization and coronary revascularization among African
American patients, given the repeatedly observed disparities in utilization
of these procedures.”