Giles
WH, Anda RF, Casper ML, Escobedo LG, Taylor HA.
Race and sex differences in rates of invasive cardiac procedures in
US hospitals. Data from the National Hospital Discharge Survey.
Arch Intern Med 1995;155(13):318-24.
This study utilized data from the National Hospital Discharge Survey for
the years 1988-1990 to compare rates of cardiac catheterization, percutaneous
transluminal coronary angioplasty (PCTA) and coronary-artery bypass surgery
(CABG) by race and sex. Those selected for the present analysis from this
nationally representative sample of hospital discharges were people at
least 35 years of age assigned a diagnosis of acute myocardial infarction.
Age was inversely related to the use of catheterization and PTCA. After
adjusting for age, the rates of cardiac catheterization, PTCA, and CABG
differed substantially by race and sex. The rates were generally highest
for white men, followed by white women, then black men, and were lowest
for black women.
The authors stratified the analysis by insurance type (in addition to
adjusting for age) in order to examine whether insurance coverage explained
part of the race and sex patterns. For cardiac catheterization, there
were no race differences among patients with private or Blue Cross health
insurance; however, there were differences among patients with Medicare,
Medicaid, or no insurance. Thus, insurance coverage may explain some of
the variation in catheterization rates by race. Also, the rates for all
the procedures for every race/sex group were lowest for those with Medicaid
or no insurance, again indicating that health insurance might be responsible
for race and gender patterns in access to cardiac procedures.
After adjusting for age, type of health insurance, hospital size and
type, region, hospital transfer (yes or no), and in-hospital mortality
rate, the odds ratios (OR) for black versus white men undergoing these
cardiac procedures were 0.61 (95% confidence interval = 0.41 to 0.91)
for catheterization, 0.31 (0.21 to 0.58) for PCTA, and 0.50 (0.44 to 0.50)
for CABG. The OR’s for black women versus white men were 0.48 (0.27-0.87)
for catheterization, 0.45 (0.19 to 1.03) for PCTA, and 0.26 (0.11 to 0.61)
for CABG. The OR’s for white women versus white men were 0.78 (0.67
to 0.92) for catheterization, 0.94 (0.72 to 1.24) for PCTA, and 0.54 (0.41
to 0.70) for CABG. These findings held when the authors matched for hospital
of admission and then adjusted for the other factors. Thus, even when
patients were admitted to the same hospital, blacks and women were less
likely than white men to undergo cardiac procedures.
Since it has been suggested that rates of procedures may vary by race
and sex due to access to cardiologists, the authors reassessed only those
patients who had undergone cardiac catheterization with regard to the
subsequent use of PTCA and CABG. The rates of PTCA did not differ significantly
by race and sex, but both black and white women had significantly lower
odds of CABG than white men. Although not statistically significant, the
overall race and sex patterns remained evident.
In their discussion, the authors consider two possible explanations for
these race and sex patterns in use of cardiac procedures that were not
specifically tested in this analysis: physician bias and patient preferences.
The authors cite the findings from the CASS study (Maynard et al 1986),
stating “(the observed racial patterns) suggest that physicians
were more aggressive in their therapeutic approach toward white patients”
and “(the observed racial patterns) could arise from differing attitudes
about risk or confidence in the medical system, or it could relate to
factors such as differences in supplemental insurance and income that
influence a patient’s ability to afford expensive procedures.”
The authors also note that they “could not determine the extent
to which these differences represent bias based on race and sex versus
the degree to which race and sex reflect other cultural and socioeconomic
factors that affect physician and patient behavior.” They do conclude,
however, that “the data from this and other studies suggest that
rates of invasive cardiac procedures are greatly influenced by the race
and sex of the patient.”