Becker
LB, Han BH, Meyer PM, Wright FA, Rhodes KV, Smith DW, Barrett J.
Racial differences in the incidence of cardiac arrest and subsequent
survival. The CPR Chicago Project.
NEJM 1993;329(9):600-6. (Comments in: ACP J Club 1994;
120 Suppl 2:47. NEJM 1993;329(9)656-8. NEJM 1994;330(3):216-7; discussion
217-8. NEJM 1994;330(3):216; discussion 217-8. NEJM 1994,330(3):217; discussion
217-8.)
The purpose of this study was to investigate “racial differences
in the incidence of cardiac arrest and of survival after cardiac arrest”
and to assess “whether these differences persist after previously
recognized risk factors are taken into account.” The data, collected
prospectively for the 6,451 incidents of out-of-hospital “nontraumatic
cardiac arrest” in Chicago, was combined from multiple sources including
hospitals, reports and questionnaires completed by paramedics, and dispatchers.
Among the victims, there were 114 survivors (2%), 439 patients who were
admitted but died in the hospital (7 %), and 5,898 patients who were pronounced
dead in emergency departments (91%).
The authors found that “in all age groups, both black men and black
women had higher rates of cardiac arrest than their white counterparts.”
In addition, blacks were less likely to survive following an episode of
cardiac arrest (0.8 % survival rate for blacks versus 2.6% for whites).
Despite higher incidence rates for the black population, the authors found
that they were less likely to be admitted to a hospital (6.3% of blacks
compared to 10.5% of whites). Of the subgroup admitted to a hospital,
“13 percent of the black patients (24 of 183) survived to discharge,
as compared with 25 percent of the white patients (84 of 336) (chi-square
= 10.2, 1 df; P=0.001).” In other words, “survival for blacks
was 52 percent of that for whites.” After controlling for response
time and initial rhythm of ventricular fibrillation or ventricular tachycardia,
“the survival rate for blacks was lower than that for whites.”
If interpreted as mortality rates, the data suggest that, in Chicago,
mortality from cardiac arrest for “blacks would be 99 percent.”
In “considering the influence of race as compared with that of
the continuous variable of age and the interval of the arrival of the
ambulance,” the investigators examined “the effect of being
black in terms of an equivalent change in these variables for a comparable
white person.” They found that “all other factors held constant,
it would require a difference of 69 years of age or of 8.3 minutes in
the time from the 911 call to the response in order to equalize the odds
for blacks and whites.”
The authors conclude that the “efforts to improve survival in the
black community begin with a detailed examination of the chain of survival
and its links: early access, early CPR, early defibrillation, and early
advanced cardiac support,” and since “cardiac arrest is often
a late manifestation of longstanding cardiovascular disease, we should
extend the chain of survival to include comprehensive health care services.”