Am Heart J 1999 May;137(5):919-27
Congestive heart failure hospitalizations and survival in California:
patterns according to race/ethnicity.
Alexander M, Grumbach K, Remy L, Rowell R, Massie BM.
Medical Effectiveness Research Center for Diverse Populations, University
of California, San Francisco, CA, USA.
BACKGROUND: Congestive heart failure (CHF) disproportionately
affects African Americans, but data are limited concerning CHF hospitalization
patterns among Hispanic and Asian populations, the 2 fastest growing ethnic
groups in the United States, and race/ethnic patterns of rehospitalization
and survival among patients with CHF are unknown. We conducted a study
to assess rates of CHF hospitalization, readmission, and survival among
diverse populations in California.
METHODS AND RESULTS: We used 2 study designs. First,
we calculated the population-based incidence of CHF hospitalization in
California in 1991. Next we conducted a retrospective cohort study that
identified patients initially hospitalized for CHF in 1991 or 1992 and
followed these patients for 12 months after their index hospitalization
to determine their likelihood of rehospitalization or death. Data were
analyzed with Cox proportional hazards models. African Americans had the
highest rate of CHF hospitalization. Age-adjusted hospitalization rates
were comparable among whites, Latinos, and Asian women and all lower than
those in African American, whereas Asian men had the lowest rates. On
adjusted analyses, African Americans were more likely than whites and
Asians to be rehospitalized (relative risk 1.07; 95% confidence interval
1.04 to 1.10). However, they were less likely to die within the 12-month
follow-up period (relative risk 0.86; 95% confidence interval 0.82 to
0.90). Whites, conversely, had the highest posthospitalization mortality
rates.
CONCLUSIONS: These findings demonstrate important racial-ethnic
differences in CHF morbidity and mortality rates. The disparate findings
of higher hospitalization and rehospitalization rates and lower mortality
rates among African Americans than whites may represent differences in
the underlying pathophysiology of CHF in these groups or differences in
access to quality care. Further studies are needed to explain these seemingly
paradoxical outcomes.
PMID: 10220642 [PubMed - indexed for MEDLINE]