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Shekelle PG, Kahan JP, Bernstein SJ, Leape LL, Kamberg CJ, Park RE.
The reproducibility of a method to identify the overuse and underuse of medical procedures.
N Engl J Med
1998;338(26):1888-95.
(Comment in: N Engl J Med. 1998;338(26):1918-20. N Engl J Med. 1998;339(20):1479-80. N Engl J Med. 1998;339(20):1479; discussion 1480-1.)

The authors performed a parallel, three-way reproducibility of the RAND-University of California at Los Angeles appropriateness method as applied to two medical procedures, coronary revascularization and hysterectomy.

“Application of individual panels’ criteria to real populations of patients resulted in a 100 percent variation in the proportion of cases classified as inappropriate and a 20 percent variation in the proportion of cases classified as necessary.”

The discussion notes the variability of physicians’ interpretations of the importance of patients’ symptoms.

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