Gordon
HS, Harper DL, Rosenthal GE.
Racial variation in predicted and observed in-hospital death. A regional
analysis.
JAMA 1996;276(20):1639-44.
This retrospective cohort study used data from 30 hospitals in northeast
Ohio to compare observed, predicted, and risk-adjusted hospital mortality
rates in white and African-American patients. The authors sought to assess
whether predicted risks of death and risk-adjusted mortality would be
similar or higher in African-Americans. The patient sample was comprised
on 88,205 patients discharged with 6 diagnoses (acute myocardial infarction,
congestive heart failure, obstructive airway disease, gastrointestinal
hemorrhage, pneumonia, and stroke) between 1991 and 1993.
Results indicated that predicted risks of death were lower in African-Americans
for 4 of the 6 diagnoses examined. (p<0.01) For all patients, the risk
of death was lower among African-American patients compared to white patients.
Examining the individual diagnoses, adjusted odds of hospital deaths were
lower in African-Americans for 2 of the 6 diagnoses (p<0.01 for congestive
heart failure and obstructive airways disease) and similar for the other
diagnoses.
The authors commented that the finding of lower severity of illness at
admission for African-Americans may reflect differences in access to care.
Specifically, African-Americans may be more likely to be admitted due
to difficulty in managing such medical problems as an outpatient or due
to the uncertainty regarding subsequent follow-up care. An alternative
explanation is that assessment of severity of illness—or predicted
mortality—differs according to race. If African-Americans undergo
diagnostic procedures less frequently, then assessed “severity”
might be lower in African-Americans and unmeasured severity (i.e. detection
bias) would be higher. By contrast, white patients might have higher “assessed”
severity as a result of adverse effects of treatment during the initial
period of hospitalization.